Before its announcement in July 2011, Lollipop Chainsaw was first mentioned as an unnamed game featuring "stylish action" in anOctober 2010 article on 1UP.com detailing Kadokawa Shoten's partnership with Grasshopper and Prope. Suda described it as featuring "really extreme twists" and being very funny. He optimistically declared that he thinks the game will be "a really big title in the worldwide market.
It is also reported that Warner Bros. Interactive Entertainment will publish the game outside of Japan and that filmmaker James Gunn has a hand in developing the game's story and characters. Gunn has said that many of the people he works with in his films and other projects are also working on Lollipop Chainsaw.
On Wednesday, February 1st, 2012, it was announced that Jimmy Urine from the electro-punk band Mindless Self Indulgence would compose the music for the boss segments. He will also provide the voice for Zed, a punk-rock themed boss.